Publications
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Berotralstat for long-term prophylaxis of hereditary angioedema in Japan: Parts 2 and 3 of the randomized APeX-J Phase III trial
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Assessment of HAE prophylaxis transition from androgen therapy to berotralstat: A subset analysis of the APeX-S trial
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The Multifactorial Impact of Receiving a Hereditary Angioedema Diagnosis
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Hereditary Angioedema Management: Individualization
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Physician and Patient Perspectives on the Management of Hereditary Angioedema: A Survey on Treatment Burden and Needs
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Caregivers’ Role in Managing Hereditary Angioedema and Perceptions of Treatment-Related Burdens
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Patient Perspectives on the Treatment Burden of Injectable Medication for Hereditary Angioedema
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Insights into the Treatment Burden of Hereditary Angioedema in the Evolving Treatment Landscape
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Time Trade‑Off Utilities for Hereditary Angioedema Health and Caregiver States
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Hereditary angioedema in children: Review and practical perspective for clinical management
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Androgen transition and management of hereditary angioedema long‑term prophylaxis in real life: a single‑center case series
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Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema
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Letter to the editor: network meta-analysis for indirect comparison of lanadelumab and berotralstat for the treatment of hereditary angioedema
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Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)
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Hereditary Angioedema Patients Would Prefer Newer-Generation Oral Prophylaxis
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Clinical Experience with Berotralstat in Patients with Hereditary Angioedema with Normal C1-Esterase Inhibitor: A Commented Case Series
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Managing Diagnosis, Treatment and Burden of Disease in Hereditary Angioedema Patients with Normal C1-Esterase Inhibitor
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Optimal Management of Hereditary Angioedema: Shared Decision-Making
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Meeting Patient Needs in Hereditary Angioedema Care
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Once-daily oral berotralstat for long-term prophylaxis of hereditary angioedema: The open-label extension of the APeX-2 randomized trial
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Specific Targeting of Plasma Kallikrein for Treatment of Hereditary Angioedema: A Revolutionary Decade
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Randomized Trial of the Efficacy and Safety of Berotralstat (BCX7353) as an Oral Prophylactic Therapy for Hereditary Angioedema: Results of APeX-2 Through 48 Weeks (Part 2)
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Oral Once-Daily Berotralstat for the Prevention of Hereditary Angioedema Attacks: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial
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Informed Decision-Making in Hereditary Angioedema Prophylaxis
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The current situation of hereditary angioedema patients in Germany: results of an online survey
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Patient and Caregiver Perspectives on Oral Transition in the Emerging Hereditary Angioedema Treatment Landscape
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Population Pharmacokinetic Modeling and Simulations of Berotralstat for Prophylactic Treatment of Attacks of Hereditary Angioedema
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Long-Term Safety and Effectiveness of Berotralstat for Hereditary Angioedema: The Open-Label APeX-S Study
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Hereditary angioedema outcomes in US patients switched from injectable long-term prophylactic medication to oral berotralstat
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A Case of Normal C1 Esterase Inhibitor Hereditary Angioedema Successfully Treated with Berotralstat
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Small Molecule Drugs for Atopic Dermatitis, Rheumatoid Arthritis, and Hereditary Angioedema
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Considerations for Transition From Subcutaneous to Oral Prophylaxis in the Treatment of Hereditary Angioedema
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Attenuated Androgen Discontinuation in Patients with Hereditary Angioedema: a Commented Case Series
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Assessment and Management of Disease Burden and Quality of Life in Patients with Hereditary Angioedema: a Consensus Report
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Long-Term Prophylaxis in Hereditary Angioedema Management: Current Practices in France and Unmet Needs
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Shared Decision-Making in the Management of Hereditary Angioedema: An Analysis of Patient and Physician Perspectives
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Global Perceptions of the Current and Future Impacts of COVID-19 on Hereditary Angioedema Management
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Berotralstat (BCX7353) is a Novel, Oral Prophylactic Treatment for Hereditary Angioedema: Review of Phase II and III Studies
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Androgen Use in Hereditary Angioedema: A Critical Appraisal and Approaches to Transitioning from Androgens to Other Therapies
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Oral Berotralstat for the Prophylaxis of Hereditary Angioedema Attacks in Patients in Japan: A Phase 3 Randomized Trial
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Expert Consensus on Prophylactic Treatment of Hereditary Angioedema
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Significant response to berotralstat in 3 patients with hereditary angioedema of unknown origin
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A Retrospective Analysis of Long-Term Prophylaxis with Berotralstat in Patients with Hereditary Angioedema and Acquired C1-Inhibitor Deficiency-Real-World Data
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Berotralstat for hereditary angioedema with C1 inhibitor deficiency: a practical guide for clinicians
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Patient-reported burden of hereditary angioedema: findings from a patient survey in the United States
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Clinical features of genetically characterized types of hereditary angioedema with normal C1 inhibitor: a systematic review of qualitative evidence
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Optimal Management of Hereditary Angioedema: Shared Decision-Making
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Definition, acronyms, nomenclature, and classification of angioedema: AAAAI, ACAAI, ACARE, and APAACI DANCE consensus
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Development and validation of a US quality of life instrument for hereditary angioedema due to C1 inhibitor deficiency
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Physician- and patient-reported outcomes by hereditary angioedema type: Data from a real-world study
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Hereditary angioedema: Epidemiology and burden of disease
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Severity of hereditary angioedema, prevalence, and diagnostic considerations
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Hereditary Angioedema
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Consequences of Insurance Coverage Delays and Denials for Patients With Hereditary Angioedema
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Prevalence of and risk factors for nutritional deficiency and food allergy in a cohort of 21 patients with Netherton syndrome
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Human papillomavirus infection in Netherton’s syndrome
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The Spectrum of Pathogenic Mutations in SPINK5 in 19 Families with Netherton Syndrome: Implications for Mutation Detection and First Case of Prenatal Diagnosis
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Kallikreins: Essential epidermal messengers for regulation of the skin microenvironment during homeostasis, repair and disease
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Netherton Syndrome in Children: Management and Future Perspectives
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Advances in understanding of Netherton syndrome and therapeutic implications
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Netherton syndrome; neuropsychological and psychosocial functioning of child and adult patients and their parents
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Netherton’s Syndrome: A Case of Two Male Siblings Diagnosed in Adulthood
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An 8-Year-Old Child with Delayed Diagnosis of Netherton Syndrome
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Netherton syndrome and papillomatous lesions—Should we perform human papilloma virus vaccination?
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Comel-Netherton syndrome: A local skin barrier defect in the absence of an underlying systemic immunodeficiency
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Characteristics of children with Netherton syndrome: a review of 21 patients
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The challenging management of a series of 43 infants with Netherton syndrome: unexpected complications and novel mutations
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Netherton Syndrome: A Genotype-Phenotype Review
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Discovery of highly potent small molecule kallikrein inhibitors
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The suprachoroidal pathway: a new drug delivery route to the back of the eye
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Microinjection via the suprachoroidal space: a review of a novel mode of administration
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Plasma Kallikrein-Kinin System as a VEGF-Independent Mediator of Diabetic Macular Edema
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Characterization of the Vitreous Proteome in Diabetes without Diabetic Retinopathy and Diabetes with Proliferative Diabetic Retinopathy
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Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation
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The Role of Plasma Kallikrein–Kinin Pathway in the Development of Diabetic Retinopathy: Pathophysiology and Therapeutic Approaches
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Kinins and Their Receptors as Potential Therapeutic Targets in Retinal Pathologies
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Plasma Kallikrein Mediates Vascular Endothelial Growth Factor-Induced Retinal Dysfunction and Thickening
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Molecules related to diabetic retinopathy in the vitreous and involved pathways
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Plasma kallikrein-kinin system and diabetic retinopathy
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The evolving therapeutic landscape of diabetic retinopathy
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Mechanisms of macular edema
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Diabetic Macular Edema: Current Understanding, Molecular Mechanisms and Therapeutic Implications
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Mechanisms of macular edema: Beyond the surface
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Diabetic Macular Edema Pathophysiology: Vasogenic versus Inflammatory